Get a ride on Pat's boat--it is well equipped and they have a lot of experience.
We took a 1 month trip to the Broughtons from Sequim, and never sat out a day because of weather. There were a couple of days when we went down wind, were no one else was moving. We did have both trim tabs and the Permatrim. We were a bit underpowered with the Honda 130. I would want at least 150, but not the weight of a 200.
On our slightly over a month, and 1200 mile trip to Alaska (launched at Prince Rupert), we sat out weather one day. But no one else was moving. The next to last day, Marie was catching too many fish, and she wanted to stay over the hole, even though the weather was building. We ended up bucking into 3 1/2 to 5 foot seas. Very slow going--we got in behind a trawler going 7 knots (but the seas slowed him to 6 or a little less, and we did fine. We would have been very slow without a larger boat to break the seas.
I agree, that the 25 will do better than a 22, but it is hard to quantitate.