We fished off the Oregon coast, and cruised big lakes and from the San Juans to Glacier Bay in our CD 22. When I retired, we decided to go for something more in the direction of the Ocean Roamer, which didn't exist yet. Wound up with a heavy deep-v diesel powered 26-footer - kinda max size reasonably towable with the Ram Cummins pickup we bought for it. Even 15 years ago, it was quite an investment.
It has a number of creature comforts, like a fridge, head and shower, lots of heat and hot water supplied by the engine, warm and always dry interior, and very comfortable ride on a short chop, that the CD 22 did not have. Since we have the time, and have discovered cruising slow, it's reasonably good at fuel economy.
If I were buying again and had the money, wanted to go fast and could live with the fuel usage, I'd have that Ocean Roamer. For far less fuel usage and more comfortable cruising, a 32 Nordic Tug. Neither one reasonably towable.
Staying towable (and fitting into our 40-foot "boat house" here in Utah), with the main mission being extended cruising at mostly slow speeds, I'd go Ranger Tug 27.
With a more limited budget, as we had 22 years ago, the CD 22 is a great compromise. What you can, and we did, do with it - for cheap - is remarkable. Pretty much the same with a Venture 23, I suppose.
Maybe the hot setup for us would be a 32 Nordic kept on a stand in Everett, and a Tom Cat kept on a trailer. Hmmm......