I know we have differing outboard engines, loads and equipment, but I did so some checking out on running the Honda 150s one at a time, or together today. I tipped the non-operating engine up just to clear the water with the prop and I had a very heavy load: Full Fuel, 2 ice chests, 4 days' food and ice, clothes, bbq's, microwave, TV, computer, painting, drawing and photography equipment, Kayak equipment, etc..
In all my tests, the fuel flow was higher for the same speed using only a single engine than using twin engines. Winds varied from 0 to 9 mph, but it appears that the single engine's need to correct the tendancy of the hull to turn while using only one engine required from .2 to .4 gallon per hour more fuel. The .4 gallon per hour difference came from running 45 degrees into, a 9 mph wind, which took more power to keep the bow from falling off. The .2 gallon per hour difference was the least noted at any direction.
I am not the exacting technician that Dr. Bob is, but here are some sample readings I jotted down: statute miles
Of course, going 6 mph got almost 4 miles per gallon both engines.
8.6mph, 2050 rpm, 3.0 gal per hour, into almost 0 mph wind.
7.9 mph, 1850 rpm, 2.2 gal per hour, into 9 mph wind.
8.2 mph 1850 rpm, 2.2 gal per hour, into 4 mph wind.
Anyway, I could get from 2.86 to 3.54 miles per gallon running around the 8 mph speed with the permatrims tipped up quite a bit - I just kept trimming them up until the rpm and speed maxed out. Also note, these measurments on not on the ocean but a very large lake, so likely less interference from waves, swells, tides, and currents. We do have some pretty good currents here, though.
Just some observations,
John