I will go against the grain on this one too. We have now trailered the Hunkydory for 70,000 miles, with a good deal of those miles on trips north to Canada & Alaska on not so good roads, with only two flat tires in all those miles & one of these happened when parked in storage with the boat off. Now what was the secret to this? Well for sure it wasn't replacing them after a manufactures or dealers recommended life span or just good luck. Three of the tires now on the trailer were manufactured in 2006 & still have decent thread with 20000 miles on them & we just returned from a trouble free 2200 mile trip last month.
What makes me replace a tire before the tread is sufficiently worn, is any sign of cracking, bulging or other defect or road damage & during the last 70000 miles several have been replaced for these reasons. It has been mentioned here before & & I think worth repeating, excessive heat is the number one destroyer of tires & this most often is caused by speed, under inflation or the combination, followed by road damage & defects, so keep the speed down, especially on hot road surface days, the inflation matched for the load they are carrying & check for proper inflation, defects & road damage often. I also have both mirror sides on the truck, set, so I can easily see the trailer tires & out of habit developed from many years ago being a professional truck driver, check them very often. Doing this, I've several times, caught slow leaks from nails or other road damage & stopped with replacement or patch before heat developed to cause a blow out.
I also think radial tires & slightly oversizing the tire for the load planned makes good since. With our duel axel trailer & the 22CD, I run the same size & load rated tire as DD does with his 23 Venture & now carry two good spares & not just on our long trips. On a duel axel trailer if you aren't able to stop very quickly, it's very likely the other tire will be stressed & possibly need replacing also.
From Michelin tire reps for off highway heavy equipment, I learned rain & wet roads especially gravel will greatly increase the tires vulnerability to puncture from a rock & he said that holds true with highway tires too. This was confirmed on a couple road trips by us in northern Canada where we drove several thousand miles on gravel & incurred 9 flat tires, most which came on rainy days & before I slowed down during them. These trips also convinced me of the justification for the extra cost in increasing the number of tire ply in those tires we had to purchase for replacement.
Mark, no recommendations from me to replace your tires now or not to. I'm simply sharing my experience as another factor to consider.
Jay