I don't have trim tabs.
I installed a Permatrim this summer after reading on this site that it smoothed out the ride in choppy water, which isn't unusual in ME coastal areas.
I definitely can cruise faster without pounding in a a chop. The Permatrim is a huge improvement at keeping the bow down and smoothing the ride in chop.
I didn't notice any change in top speed or WOT RPM.
But...., there's often a but. I did experience a downside. When cruising at high speed, if 2 -3 people run to one side to check out a seal, eagle, or other sight, the boat will swerve and turning the steering wheel normally will not correct it. It seems as though the heeling due to the weight shift makes the Permatrim act like a rudder and causes the boat to turn on its own.
I had experienced some minor slews when Carol ran to take photos during our downeast cruise, but didn't recognize the cause. While cruising with another couple on board, the current seemed to be setting us to port toward a buoy in Hockamock Bay. I turned the wheel to stbd. 3 people then suddenly went to the stbd side to check out a seal, causing the boat to go to port toward the buoy. I had to really crank the wheel to veer away from the buoy. I never experienced anything like that before the Permatrim.
So, from my experience it seems like the Permatrim can act like a rudder during heeling situations at high speed.
Rick from Maine