Could not tell from prior posts if anyone was using twin Permatrims - Does anyone run Permatrims on Twin Hondas on a CD22? If so can you adjust the angle of each engine to get the port to starboard balance that most adjust with trim tabs."
You can use two engines with Permatrims to trim a boat, but the separation of the motors is not as great as the trim tabs, and more trim angle is needed for the same effect for lateral trim. Differential trim like that on the motors will usually be less efficient than trim tabs, effecting gas mileage.
Also - I have read here that in a following sea you want the trim tabs up. - how does that apply to Permatrims - is there any danger issue to Permatrims in certain sea conditions that trim tabs would help?
You'd get much the same effect on the Permatrims being lifted by a wave approaching from the rear that you would with trim tabs. With trim tabs, they can be raised up pretty much out of the way. The motor trim can be done similarly, but now you're affecting thrust angle, too. You certainly don't want both of them down in a following sea with appreciable wave height. The trim tabs won't cancel out any bad lift from the Permatrims. Putting them down to do so is in the wrong direction and compounds the problem. A lot depends on your boat loading and, of course, the sea state and your skill level. If you want them both, try it out. If they lift too much in your conditions and the ride gets really squirley, you have to give something up, probably the Permatrims.
Some folks who have them both say that Permatrims are not necessary or beneficial once you have trim tabs, and it's nice to be able to trim the boat with the tabs and use the motor to adjust the thrust angle for efficiency and gas mileage w/o overtrimming the boat!