What is the condition of the current deck? Is the entire core rotten? Have you drilled test holes from underneath? How do you know that the entire core has to be replaced?
Replacing a bow deck on any boat is not easy! Are you gong to keep the top mold layer and laminate from underneath, turn the boat upside down (I am serious) and then weight the core material as you let the resin set up? (This is the way the deck is constructed, and a common method used for smaller boats) or take the top molding off, and totally reconstruct it--which means a lot of fairing, and then formation of nonskid, with a mold? (We rolled out the nonskid on the cockpit floor on the 25--but that was the way it was done originally. although this could be done on the foredeck, it is more labor intensive.)
If working from inside, consider the issue of fumes when laminating--you will be best off with a positive pressure respiratory system.
I have never worked with Canacore. It is very similar to Nida Core (which I have used for the deck replacement in the cockpit of the C Dory 25)/ For these cores to be most effective they should have a scim of fiberglass mat on the surfaces. I don't see where the canacore has this...but it may?
How thick is the bow deck of your 16? My recollection of the 22's is that it is about 3/4" core--no more than 1" core--balsa. Balsa remains a very good core material. It has many times the shear strength of Canacore.
The thicker the sandwich, the more rigidity it will have. There may be a point of overkill; probably 1.5" Canacore is overkill. There are several ways to put in core material, where there is a curve. One is to kerf the material (as you suggested--(without a scrim, this is going to be very difficult), the other way is to use several thinner layers, with a layer of mat between, and that is generally better. Baltek end grain Balsa has enough flexibility, because of the way the blocks are laid, that it can accommodate moderate curves--and I believe that is what was used in the 16 of your vintage. Balsa has good adherence to fiberglass resin.
No matter what core material, you need to put epoxy around any bolt holes--including the bow railing bolts, anchor roller pulpit, cleats etc. If you are using balsa core, you will get indefinite life, if it is properly done. I cut up some boats which were over 30 years old which had balsa decks, and they were was good as the day they were laminated, when properly sealed. (Part of our core laminate study post Hurricane Ivan; in development of ultrasonic measurement tools for boat laminates.)