I have the earlier model radio (without internal GPS), and it's connected to my Garmin GPSMAP via the older NMEA 283 (I believe) system. Works well. Hardest part is just figuring out which wires connect to which wires. Have wiring diagrams from both your radio and MFD, and study closely which tiny wire is which. If you're MFD is like my GPSMAP 541 or 840, you can turn the AIS repeater on or off. It is definitely nice having the targets pop up on the larger MFD screen, than the tiny VHF screen. But if you are in a crowded marina where everyone seems to leave their AIS on, it's also nice to turn off the display of targets. If both your electronics have the newer 2000 network system, it's just easy plug and play, if you have the proper backbone cables. Colby