Feasible? Sure--some have come from as far as San Francisco, a multi-day trip by water. Would I do it? No, for two reasons: 1) Too many on-the-water miles, and 2) Prevailing NW winds would put you straight into the chop and swells--however, leaving at daybreak would most likely avoid most of that if you watch the weather, 60-70 nm(?) is a long slog. The main group launches from Marina Del Rey, nice ramps, and parking area relatively secure with regular police patrols, 30+ nm, and the waters in that area tend to be decent. I like San Pedro, Cabrillo Beach launch ramp, but a little iffy on the security, although I've never had a problem in the 40+ years I've used that area-YMMV, 20 nm. Others have launched out of Long Beach, but I'm not familiar, 25 nm?. And some have launched out of Dana Point, but again not familiar, 40+ nm and mostly into the prevailing winds again.