I will say that adding a second battery to my starboard lazarette was an interesting endeavor. I had my kicker on the same side and moved it port, so the boat is more balanced now (slightly heavy on the battery side), but with more weight in the stern (and the kicker farther aft than it was) the boat does handle and behave differently. Most notably, if 2 or 3 adults want to ride in the cockpit instead of the cabin it can be tough to get on step when fully loaded.
I would actually like to put my batteries under my sink, and have a couple items that run straight to the battery intersect there. It's way down my list right now, but it did make a difference. Overall I'm happy with where everything is set up, and I think if I buy lighter batteries when the time comes (and maybe a lighter kicker too) I'll be perfectly happy.